Biphasic electrical stimulation: A strategy may bring hope to spinal cord injury patients

Transplantation stem cells is a potential clinical therapy for repair of spinal cord injury. However, transplanted cells are especially vulnerable due to a lack of sufficient growth factors at the transplant site. The present study demonstrates that Biphasic electrical stimulation (BES) prevents growth factor-deprived apoptosis through the BDNF-PI3K/Akt signaling in neural stem cells. The findings may guide future efforts to stem cell-based transplantation therapy. It also raises hope that BES m…

Fuente : http://www.eurekalert.org/pub_releases/2013-08/sfe…