Engineered T cells kill tumors but spare normal tissue in an animal model

Researchers devised a next gen cancer immune approach in which the activation signal for T cells is physically dissociated from a second costimulatory signal for immune cells. The two CARs carry different antigen specificity — mesothelin and a-folate receptor. Mesothelin is primarily associated with mesothelioma and ovarian cancer, and a-folate receptor with ovarian cancer.

Fuente : http://www.eurekalert.org/pub_releases/2013-04/uop…