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Failure to destroy toxic protein — not buildup of protein itself — contributes to Huntington’s disease

Neurodegenerative diseases are often associated with the buildup of toxic proteins that lead to the death of neurons. But now, scientists at the Gladstone Institutes have discovered that the progression of disease is not due to the buildup of toxins itself, but rather in the individual neurons’ ability to flush these toxins out. Further, they have identified a therapeutic target that could boost this ability, thereby protecting the brain from the diseases’ deadly effects.

Fuente : http://www.eurekalert.org/pub_releases/2013-07/gi-…

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