How DNA repair helps prevent cancer

DNA damage is a natural biological occurrence that happens every time cells divide and multiply; thus, DNA repair is important for preserving the composition of the genome. Michael Feig at Michigan State University uses supercomputing to study the molecular-level dynamics involved in this process. The MutS and MSH2-MSH6 proteins are responsible for recognizing defective DNA. Bent DNA is a key factor in recognizing mismatches. This research was published in the Journal of Physical Chemistry B (Ap…

Fuente : http://www.eurekalert.org/pub_releases/2013-08/uot…