Impact of stem cell transplantation location in brain a crucial factor for cell survival

Researchers found that nonself-donated cells better survive implantation into brains of immunocompetent research mice when grafts are injected into the striatum (STR) of the brain rather than injected into the forceps minor (FM) region. All FM grafts were rejected; STR grafts accumulated and survived along the border between the striatum and the corpus callosum. Researchers concluded that allograft survival within the CNS of an immunocompetent, non-immune suppressed host may be dependent on imp…

Fuente : http://www.eurekalert.org/pub_releases/2013-02/ctc…



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